Novel statistical methodology reveals that hip shape is associated with incident radiographic hip osteoarthritis among African American women.

ABSTRACT:

Introduction

Hip shape is a risk factor for the development of hip osteoarthritis (OA), and current methods to assess hip shape from radiographs are limited; therefore this study explored current and novel methods to assess hip shape.

Methods

Data from a prior case-control study nested in the Johnston County OA Project were used, including 382 hips (from 342 individuals). Hips were classified by radiographic hip OA (RHOA) status as RHOA cases (baseline Kellgren Lawrence grade [KLG] 0 or 1, follow-up [mean 6 years] KLG ≥ 2) or controls (KLG = 0 or 1 at both baseline and follow-up). Proximal femur shape was assessed using a 60-point model as previously described. The current analysis explored commonly used principal component analysis (PCA), as well as novel statistical method

SUBMITTER: An H 

PROVIDER: S-EPMC4799754 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature