A prospective study of appetite and food craving in 30 patients with Cushing's disease.

ABSTRACT:

Context

Glucocorticoid (GC) exposure increases food intake, but the mechanisms in humans are not known. Investigation of appetite and food craving has not been done in patients with chronic GC exposure due to Cushing's disease (CD), either before or after treatment, and could provide insight into mechanisms of food intake and obesity in these patients.

Purpose

To examine whether surgical remission of CD changes appetite (prospective consumption, hunger, satisfaction, and fullness) and food cravings (sweet, salty, fatty, and savory); and to identify predictors of appetite and craving in CD remission.

Methods

30 CD patients, mean age 40.0 years (range 17-70), mean BMI 32.3 ± 6.4, were prospectively studied before and at a mean of 17.4 mo. after remission. At each visit

SUBMITTER: Geer EB 

PROVIDER: S-EPMC4799764 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature