Falsification Testing of Instrumental Variables Methods for Comparative Effectiveness Research.

ABSTRACT:

Objectives

To demonstrate how falsification tests can be used to evaluate instrumental variables methods applicable to a wide variety of comparative effectiveness research questions.

Study design

Brief conceptual review of instrumental variables and falsification testing principles and techniques accompanied by an empirical application. Sample STATA code related to the empirical application is provided in the Appendix.

Empirical application

Comparative long-term risks of sulfonylureas and thiazolidinediones for management of type 2 diabetes. Outcomes include mortality and hospitalization for an ambulatory care-sensitive condition. Prescribing pattern variations are used as instrumental variables.

Conclusions

Falsification testing is an easily computed and power

SUBMITTER: Pizer SD 

PROVIDER: S-EPMC4799892 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature