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Pediatric Acute Respiratory Distress Syndrome: Fluid Management in the PICU.


ABSTRACT: The administration of an appropriate volume of intravenous fluids, while avoiding fluid overload, is a major challenge in the pediatric intensive care unit. Despite our efforts, fluid overload is a very common clinical observation in critically ill children, in particular in those with pediatric acute respiratory distress syndrome (PARDS). Patients with ARDS have widespread damage of the alveolar-capillary barrier, potentially making them vulnerable to fluid overload with the development of pulmonary edema leading to prolonged course of disease. Indeed, studies in adults with ARDS have shown that an increased cumulative fluid balance is associated with adverse outcome. However, age-related differences in the development and consequences of fluid overload in ARDS may exist due to disparitie

SUBMITTER: Ingelse SA 

PROVIDER: S-EPMC4800174 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature