Biomarkers of Kidney Injury Among Nicaraguan Sugarcane Workers.

ABSTRACT:

Background

In Central America, an epidemic of chronic kidney disease of unknown cause disproportionately affects young male agricultural workers.

Study design

Longitudinal cohort study.

Setting & participants

284 sugarcane workers in 7 jobs were recruited from one company in northwestern Nicaragua. Blood and urine samples were collected before and near the end of the 6-month harvest season.

Predictors

Job category (cane cutter, seeder, seed cutter, agrichemical applicator, irrigator, driver, and factory worker); self-reported water and electrolyte solution intake.

Outcomes & measurements

Changes in levels of urinary kidney injury biomarkers normalized to urine creatinine level, including neutrophil gelatinase-associated lipocalin (NGAL), interleukin 18 (

SUBMITTER: Laws RL 

PROVIDER: S-EPMC4801230 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature