Evolutionary and developmental implications of asymmetric brain folding in a large primate pedigree.

ABSTRACT: Bilateral symmetry is a fundamental property of the vertebrate central nervous system. Local deviations from symmetry provide various types of information about the development, evolution, and function of elements within the CNS, especially the cerebral hemispheres. Here, we quantify the pattern and extent of asymmetry in cortical folding within the cerebrum of Papio baboons and assess the evolutionary and developmental implications of the findings. Analyses of directional asymmetry show a population-level trend in length measurements indicating that baboons are genetically predisposed to be asymmetrical, with the right side longer than the left in the anterior cerebrum while the left side is longer than the right posteriorly. We also find a corresponding bias to display a right frontal pe

SUBMITTER: Atkinson EG 

PROVIDER: S-EPMC4801758 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature