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Constrained Total Energy Expenditure and Metabolic Adaptation to Physical Activity in Adult Humans.


ABSTRACT: Current obesity prevention strategies recommend increasing daily physical activity, assuming that increased activity will lead to corresponding increases in total energy expenditure and prevent or reverse energy imbalance and weight gain [1-3]. Such Additive total energy expenditure models are supported by exercise intervention and accelerometry studies reporting positive correlations between physical activity and total energy expenditure [4] but are challenged by ecological studies in humans and other species showing that more active populations do not have higher total energy expenditure [5-8]. Here we tested a Constrained total energy expenditure model, in which total energy expenditure increases with physical activity at low activity levels but plateaus at higher activity levels as the

SUBMITTER: Pontzer H 

PROVIDER: S-EPMC4803033 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature