Randomized Trial of Apneic Oxygenation during Endotracheal Intubation of the Critically Ill.

ABSTRACT:

Rationale

Hypoxemia is common during endotracheal intubation of critically ill patients and may predispose to cardiac arrest and death. Administration of supplemental oxygen during laryngoscopy (apneic oxygenation) may prevent hypoxemia.

Objectives

To determine if apneic oxygenation increases the lowest arterial oxygen saturation experienced by patients undergoing endotracheal intubation in the intensive care unit.

Methods

This was a randomized, open-label, pragmatic trial in which 150 adults undergoing endotracheal intubation in a medical intensive care unit were randomized to receive 15 L/min of 100% oxygen via high-flow nasal cannula during laryngoscopy (apneic oxygenation) or no supplemental oxygen during laryngoscopy (usual care). The primary outcome was lowest a

SUBMITTER: Semler MW 

PROVIDER: S-EPMC4803060 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature