Thiazide-Associated Hypercalcemia: Incidence and Association With Primary Hyperparathyroidism Over Two Decades.

ABSTRACT:

Context

Thiazide diuretics, the antihypertensive agent prescribed most frequently worldwide, are commonly associated with hypercalcemia. However, the epidemiology and clinical features are poorly understood.

Objective

To update the incidence of thiazide-associated hypercalcemia and clarify its clinical features.

Patients and methods

In a population-based descriptive study, Olmsted County, Minnesota, residents with thiazide-associated hypercalcemia were identified through the Rochester Epidemiology Project and the Mayo Clinic Laboratory Information System from 2002-2010 and were added to the historical cohort beginning in 1992.

Main outcome

Incidence rates were adjusted to the 2010 United States white population.

Results

Overall, 221 Olmsted County reside

SUBMITTER: Griebeler ML 

PROVIDER: S-EPMC4803175 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature