Effects of Renal Denervation on Renal Artery Function in Humans: Preliminary Study.

ABSTRACT:

Aim

To study the effects of RD on renal artery wall function non-invasively using magnetic resonance.

Methods and results

32 patients undergoing RD were included. A 3.0 Tesla magnetic resonance of the renal arteries was performed before RD and after 6-month. We quantified the vessel sharpness of both renal arteries using a quantitative analysis tool (Soap-Bubble®). In 17 patients we assessed the maximal and minimal cross-sectional area of both arteries, peak velocity, mean flow, and renal artery distensibility. In a subset of patients wall shear stress was assessed with computational flow dynamics. Neither renal artery sharpness nor renal artery distensibility differed significantly. A significant increase in minimal and maximal areas (by 25.3%, p = 0.008, and 24.6%, p = 0.0

SUBMITTER: Doltra A 

PROVIDER: S-EPMC4803336 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature