Oculomotor executive function abnormalities with increased tic severity in Tourette syndrome.

ABSTRACT:

Background

Reports conflict as to whether Tourette syndrome (TS) confers deficits in executive function. This study's aim was to evaluate executive function in youths with TS using oculomotor tasks while controlling for confounds of tic severity, age, medication, and severity of comorbid disorders.

Method

Four saccade tasks requiring the executive functions of response generation, response inhibition, and working memory (prosaccade, antisaccade, 0-back, and 1-back) were administered. Twenty youths with TS and low tic severity (TS-low), nineteen with TS and moderate tic severity (TS-moderate), and 29 typically developing control subjects (Controls) completed the oculomotor tasks.

Results

There were small differences across groups in the prosaccade task. Controlling for

SUBMITTER: Jeter CB 

PROVIDER: S-EPMC4803434 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature