Two Randomized Controlled Pilot Trials of Social Forces to Improve Statin Adherence among Patients with Diabetes.

ABSTRACT:

Background

Medication nonadherence is an important obstacle to cardiovascular disease management.

Objective

To improve adherence through real-time feedback based on theories of how social forces influence behavior.

Design

Two randomized controlled pilot trials called PROMOTE and SUPPORT. Participants stored statin medication in wireless-enabled pill bottles that transmitted adherence data to researchers.

Participants

Adults with diabetes and a history of low statin adherence based on pharmacy refills (i.e., Medication Possession Ratio [MPR] <80% in the pre-randomization screening period).

Intervention

In PROMOTE, each participant was randomized to 1) weekly messages in which that participant's statin adherence was compared to that of other participants (

SUBMITTER: Reese PP 

PROVIDER: S-EPMC4803690 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature