Sleep disturbance due to heartburn and regurgitation is common in patients with functional dyspepsia.

ABSTRACT:

Background

Reflux symptoms (heartburn and regurgitation) are common in patients with functional dyspepsia who do not have gastroesophageal reflux disease (GERD).

Objective

The purpose of this study was to assess the relationship of reflux symptoms with sleep disturbances in patients with functional dyspepsia without GERD and in those with GERD.

Methods

This post-hoc analysis of data from the Diamond study (NCT00291746) included patients with frequent upper gastrointestinal symptoms, of whom 137 had functional dyspepsia and 193 had GERD (diagnosed by endoscopy and pH monitoring). Patients completed symptom questionnaires and were interviewed by physicians.

Results

During the seven nights before study entry, 46.0% of patients with functional dyspepsia and 64.8% o

SUBMITTER: Vakil N 

PROVIDER: S-EPMC4804370 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature