Partially reduced graphene oxide based FRET on fiber-optic interferometer for biochemical detection.

ABSTRACT: Fluorescent resonance energy transfer (FRET) with naturally exceptional selectivity is a powerful technique and widely used in chemical and biomedical analysis. However, it is still challenging for conventional FRET to perform as a high sensitivity compact sensor. Here we propose a novel 'FRET on Fiber' concept, in which a partially reduced graphene oxide (prGO) film is deposited on a fiber-optic modal interferometer, acting as both the fluorescent quencher for the FRET and the sensitive cladding for optical phase measurement due to refractive index changes in biochemical detection. The target analytes induced fluorescence recovery with good selectivity and optical phase shift with high sensitivity are measured simultaneously. The functionalized prGO film coated on the fiber-optic interfer

SUBMITTER: Yao BC 

PROVIDER: S-EPMC4806316 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature