Multiple genomic signatures of selection in goats and sheep indigenous to a hot arid environment.

ABSTRACT: Goats and sheep are versatile domesticates that have been integrated into diverse environments and production systems. Natural and artificial selection have shaped the variation in the two species, but natural selection has played the major role among indigenous flocks. To investigate signals of natural selection, we analyzed genotype data generated using the caprine and ovine 50K SNP BeadChips from Barki goats and sheep that are indigenous to a hot arid environment in Egypt's Coastal Zone of the Western Desert. We identify several candidate regions under selection that spanned 119 genes. A majority of the genes were involved in multiple signaling and signal transduction pathways in a wide variety of cellular and biochemical processes. In particular, selection signatures spanning several g

SUBMITTER: Kim ES 

PROVIDER: S-EPMC4806575 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature