The risk of smoking on multiple sclerosis: a meta-analysis based on 20,626 cases from case-control and cohort studies.

ABSTRACT: Background. Multiple sclerosis (MS) has become a disease that represents a tremendous burden on patients, families, and societies. The exact etiology of MS is still unclear, but it is believed that a combination of genetic and environmental factors contribute to this disease. Although some meta-analyses on the association between smoking and MS have been previously published, a number of new studies with larger population data have published since then. Consequently, these additional critical articles need to be taken into consideration. Method. We reviewed articles by searching in PubMed and EMBASE. Both conservative and non-conservative models were used to investigate the association between smoking and the susceptibility to MS. We also explored the effect of smoking on the susceptibilit

SUBMITTER: Zhang P 

PROVIDER: S-EPMC4806598 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature