Racial Differences in and Prognostic Value of Biomarkers of Hyperglycemia.

ABSTRACT:

Objective

We compared levels and associations of traditional (fasting glucose, HbA1c) and nontraditional (fructosamine, glycated albumin, and 1,5-anhydroglucitol [1,5-AG]) biomarkers of hyperglycemia with incident cardiovascular disease (CVD), incident end-stage renal disease (ESRD), and prevalent retinopathy in black and white adults.

Research design and methods

We included 10,373 participants without (8,096 white, 2,277 black) and 727 with diagnosed diabetes (425 white, 302 black) from the Atherosclerosis Risk in Communities (ARIC) Study. We used Cox proportional hazards models to compare hazards ratios of CVD and ESRD among blacks and whites from baseline (1990-1992) through 2012. We compared the odds ratios (from logistic regression) of retinopathy among blacks and white

SUBMITTER: Parrinello CM 

PROVIDER: S-EPMC4806772 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature