Chondroitin sulfate is involved in the hypercalcification of the organic matrix of bovine peritubular dentin.

ABSTRACT: Apatitic mineral of dentin forms within the collagenous matrix (intertubular dentin, ITD) secreted from the odontoblastic processes (OP). Highly calcified mineral (peritubular dentin, PTD) is deposited at the interface between the ITD and each process membrane, creating a tubular system penetrating the dentin that extends from the dentino-enamel junction to the predentin-dentin junction. We focus on determining the composition of the PTD both with regard to its organic matrix and the inorganic phase. A laser capture technique has been adapted for the isolation of the mineralized PTD free from the ITD, and for the analysis of the PTD by SEM, TEM, and energy dispersive spectrometry (EDS), these data were subsequently compared with similar analyses of intact dentin slices containing ITD bound

SUBMITTER: Dorvee JR 

PROVIDER: S-EPMC4806796 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature