Investigation of the Genetics and Biochemistry of Roseobacticide Production in the Roseobacter Clade Bacterium Phaeobacter inhibens.

ABSTRACT: Roseobacterclade bacteria are abundant in surface waters and are among the most metabolically diverse and ecologically significant species. This group includes opportunistic symbionts that associate with micro- and macroalgae. We have proposed that one representative member,Phaeobacter inhibens, engages in a dynamic symbiosis with the microalgaEmiliania huxleyi In one phase, mutualistically beneficial molecules are exchanged, including theRoseobacter-produced antibiotic tropodithietic acid (TDA), which is thought to protect the symbiotic interaction. In an alternative parasitic phase, triggered by algal senescence, the bacteria produce potent algaecides, the roseobacticides, which kill the algal host. Here, we employed genetic and biochemical screens to identify the roseobacticide biosynth

SUBMITTER: Wang R 

PROVIDER: S-EPMC4807370 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature