Poly-arginine conjugated triarylmethyl radical as intracellular spin label.

ABSTRACT: Stable triarylmethyl radicals are ideal spin labels used for biomedical electron paramagnetic resonance applications. Previously reported structures exhibit polar charged functions for water solubilization preventing them from crossing the cell membrane. We report the synthesis of a triarylmethyl radical conjugated to poly-arginine peptide allowing intracellular delivery of the paramagnetic label.

SUBMITTER: Driesschaert B 

PROVIDER: S-EPMC4807691 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature