Persistence with secondary prevention medications after acute myocardial infarction: Insights from the TRANSLATE-ACS study.

ABSTRACT:

Background

Persistent use of secondary prevention therapies after acute myocardial infarction (MI) is critical to optimizing long-term outcomes.

Methods

Medication persistence was assessed among 7,955 MI patients in 216 hospitals participating in the Treatment with Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome study from 2010 to 2012. Persistence was defined as continuation of aspirin, adenosine diphosphate receptor inhibitors, β-blockers, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, and statins from discharge to 6 months post-MI. Multivariable logistic regression modeling was used to determine factors associated with nonpersistence, defined as <80% persistence with

SUBMITTER: Mathews R 

PROVIDER: S-EPMC4808054 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature