A history of preeclampsia is associated with a risk for coronary artery calcification 3 decades later.

ABSTRACT:

Background

A history of preeclampsia is an independent risk factor for cardiac events and stroke. Changes in vasculature structure that contribute to these associations are not well understood.

Objective

The aim of this study was to quantify coronary artery calcification (CAC), a known risk factor for cardiac events, in a prospective cohort of women with and without histories of preeclampsia.

Study design

Women without prior cardiovascular events (40 with and 40 without histories of preeclampsia, matched for parity and age at index birth) were recruited from a large population-based cohort of women who were residents of Olmsted County, Minnesota, and who delivered from 1976 through 1982. Computed tomography was performed to measure CAC in Agatston units. All pregnancy

SUBMITTER: White WM 

PROVIDER: S-EPMC4808608 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature