POPE study: rationale and methodology of a study to phenotype patients with COPD in Central and Eastern Europe.

ABSTRACT:

Introduction

Chronic obstructive pulmonary disease (COPD) constitutes a major health challenge in Central and Eastern European (CEE) countries. However, clinical phenotypes, symptom load, and treatment habits of patients with COPD in CEE countries remain largely unknown. This paper provides a rationale for phenotyping COPD and describes the methodology of a large study in CEE.

Methods/design

The POPE study is an international, multicenter, observational cross-sectional survey of patients with COPD in CEE. Participation in the study is offered to all consecutive outpatients with stable COPD in 84 centers across the CEE region if they fulfill the following criteria: age >40 years, smoking history ≥10 pack-years, a confirmed diagnosis of COPD with postbronchodilator FEV1/FVC <0

SUBMITTER: Zbozinkova Z 

PROVIDER: S-EPMC4809323 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature