Cortical Thinning in Healthy Aging Correlates with Larger Motor-Evoked EEG Desynchronization.

ABSTRACT: Although electroencephalography (EEG) is a valuable tool to investigate neural activity in patients and controls, exactly how local anatomy impacts the measured signal remains unclear. Better characterizing this relationship is important to improve the understanding of how inter-subject differences in the EEG signal are related to neural activity. We hypothesized that cortical structure might affect event-related desynchronization (ERD) in EEG. Since aging is a well-documented cause of cortical thinning, we investigated the effects of cortical thickness (CT) and cortical depth (CD - the skull-to-cortex distance) on ERD using anatomical MRI and motor-evoked EEG in 17 healthy young adults and 20 healthy older persons. Results showed a significant negative correlation between ERD and CT, but

SUBMITTER: Provencher D 

PROVIDER: S-EPMC4809888 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature