Treatment of patients with multifocal motor neuropathy with immunoglobulins in clinical practice: the SIGNS registry.

ABSTRACT:

Objectives

The management of patients with multifocal motor neuropathy (MMN) under everyday clinical conditions has been insufficiently studied. We therefore collected comprehensive observational data on patients with MMN who received intravenous (IV) or subcutaneous (SC) immunoglobulins (IGs) as maintenance therapy.

Methods

This was a prospective, noninterventional study (registry) in neurological centres (hospitals and offices) throughout Germany.

Results

As of 1 December 2015, 80 patients with MMN were included (mean age 55.4 ± 9.8 years, 67% males, mean disease duration 10.7 ± 10.2 years). The affected limb regions were predominantly distal muscle groups of the upper extremities. On the inflammatory neuropathy cause and treatment (INCAT) scale, 94% of the patients

SUBMITTER: Stangel M 

PROVIDER: S-EPMC4811011 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature