Laterality of Brain Activation for Risk Factors of Addiction.

ABSTRACT:

Background

Laterality of brain activation is reported for tests of risk factors of addiction- impulsivity and craving-but authors rarely address the potential significance of those asymmetries.

Objective

The purpose of this study is to demonstrate this laterality and discuss its relevance to cognitive and neurophysiological asymmetries associated with drug abuse vulnerability in order to provide new insights for future research in drug abuse.

Method

From published reports, brain areas of activation for two tests of response inhibition or craving for drugs of abuse were compiled from fMRI activation peaks and were tabulated for eight sections (octants) in each hemisphere. Percent asymmetries were calculated (R-L/R+L) across studies for each area.

Results

For imp

SUBMITTER: Gordon HW 

PROVIDER: S-EPMC4811731 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature