Lung function decline over 25 years of follow-up among black and white adults in the ARIC study cohort.

ABSTRACT:

Background

Interpretation of longitudinal information about lung function decline from middle to older age has been limited by loss to follow-up that may be correlated with baseline lung function or the rate of decline. We conducted these analyses to estimate age-related decline in lung function across groups of race, sex, and smoking status while accounting for dropout from the Atherosclerosis Risk in Communities Study.

Methods

We analyzed data from 13,896 black and white participants, aged 45-64 years at the 1987-1989 baseline clinical examination. Using spirometry data collected at baseline and two follow-up visits, we estimated annual population-averaged mean changes in forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) by race, sex, and smokin

SUBMITTER: Mirabelli MC 

PROVIDER: S-EPMC4811733 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature