Relation between stress and cytokine responses in inner-city mothers.

ABSTRACT:

Background

Women in poor urban neighborhoods have high rates of stress and allergic diseases, but whether stress or stress correlates such as depression promote inflammatory and type 2 cytokine responses is unknown.

Objective

To examine associations among external stressors, perceived stress, depression, and peripheral blood mononuclear cell cytokine responses of mothers enrolled in the Urban Environment and Childhood Asthma Study and test the hypothesis that stress would be positively associated with type 2 and selected proinflammatory (tumor necrosis factor-α and interleukin-8) responses.

Methods

Questionnaire data from mothers living in 4 inner cities included information about external stress, stress perception, and depression. The external stress domains (interpe

SUBMITTER: Gruenberg DA 

PROVIDER: S-EPMC4814156 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature