Association between adiposity and cognitive function in young men: Hormonal mechanisms.

ABSTRACT:

Objective

To determine the association between adiposity, hormones, and cognition in young men with abdominal obesity.

Methods

In this cross-sectional observational study, 53 nondiabetic men with abdominal obesity (mean body mass index, 37.3 kg/m(2) ; age, 22-45 years) and normal intelligence underwent detailed measures of body composition, hormonal profiles, and cognition. Age- and education-adjusted performance in five cognitive domains was examined.

Results

Total fat percentage was negatively associated with visuospatial skills (P = 0.002) and visual memory (P = 0.012). Insulin resistance (homeostatic model assessment of insulin resistance) was also negatively associated with these domains (P = 0.05 and trend, P = 0.06, respectively). Total testosterone levels were

SUBMITTER: Bove RM 

PROVIDER: S-EPMC4814338 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature