Cost-effectiveness of Crohn's disease post-operative care.

ABSTRACT:

Aim

To define the cost-effectiveness of strategies, including endoscopy and immunosuppression, to prevent endoscopic recurrence of Crohn's disease following intestinal resection.

Methods

In the "POCER" study patients undergoing intestinal resection were treated with post-operative drug therapy. Two thirds were randomized to active care (6 mo colonoscopy and drug intensification for endoscopic recurrence) and one third to drug therapy without early endoscopy. Colonoscopy at 18 mo and faecal calprotectin (FC) measurement were used to assess disease recurrence. Administrative data, chart review and patient questionnaires were collected prospectively over 18 mo.

Results

Sixty patients (active care n = 43, standard care n = 17) were included from one health service. Median

SUBMITTER: Wright EK 

PROVIDER: S-EPMC4814750 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature