Assessment of potential public health impact of a quadrivalent inactivated influenza vaccine in Thailand.

ABSTRACT:

Background

Each year, an influenza B strain representing only one influenza B lineage is included in the trivalent inactivated influenza vaccine (IIV3); a mismatch between the selected lineage and circulating viruses can result in suboptimal vaccine effectiveness. We modeled the added potential public health impact of a quadrivalent inactivated influenza vaccine (IIV4) that includes strains from both influenza B lineages compared to IIV3 on influenza-associated morbidity and mortality in Thailand.

Methods

Using data on the incidence of influenza-associated hospitalizations and deaths, vaccine effectiveness, and vaccine coverage from the 2007-2012 influenza seasons in Thailand, we estimated rates of influenza-associated outcomes that might be averted using IIV4 instead of IIV

SUBMITTER: Kittikraisak W 

PROVIDER: S-EPMC4814859 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature