Mining the pig genome to investigate the domestication process.

ABSTRACT: Pig domestication began around 9000 YBP in the Fertile Crescent and Far East, involving marked morphological and genetic changes that occurred in a relatively short window of time. Identifying the alleles that drove the behavioural and physiological transformation of wild boars into pigs through artificial selection constitutes a formidable challenge that can only be faced from an interdisciplinary perspective. Indeed, although basic facts regarding the demography of pig domestication and dispersal have been uncovered, the biological substrate of these processes remains enigmatic. Considerable hope has been placed on new approaches, based on next-generation sequencing, which allow whole-genome variation to be analyzed at the population level. In this review, we provide an outline of the cu

SUBMITTER: Ramos-Onsins SE 

PROVIDER: S-EPMC4815588 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature