Effect of restrictive versus liberal transfusion strategies on outcomes in patients with cardiovascular disease in a non-cardiac surgery setting: systematic review and meta-analysis.

ABSTRACT:

Objective

To compare patient outcomes of restrictive versus liberal blood transfusion strategies in patients with cardiovascular disease not undergoing cardiac surgery.

Design

Systematic review and meta-analysis.

Data sources

Randomised controlled trials involving a threshold for red blood cell transfusion in hospital. We searched (to 2 November 2015) CENTRAL, Medline, Embase, CINAHL, PubMed, LILACS, NHSBT Transfusion Evidence Library, ClinicalTrials.gov, WHO International Clinical Trials Registry Platform, ISRCTN Register, and EU Clinical Trials Register. Authors were contacted for data whenever possible.

Trial selection

Published and unpublished randomised controlled trials comparing a restrictive with liberal transfusion threshold and that included patients

SUBMITTER: Docherty AB 

PROVIDER: S-EPMC4817242 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature