Bacteria, phages and pigs: the effects of in-feed antibiotics on the microbiome at different gut locations.

ABSTRACT: Disturbance of the beneficial gut microbial community is a potential collateral effect of antibiotics, which have many uses in animal agriculture (disease treatment or prevention and feed efficiency improvement). Understanding antibiotic effects on bacterial communities at different intestinal locations is essential to realize the full benefits and consequences of in-feed antibiotics. In this study, we defined the lumenal and mucosal bacterial communities from the small intestine (ileum) and large intestine (cecum and colon) plus feces, and characterized the effects of in-feed antibiotics (chlortetracycline, sulfamethazine and penicillin (ASP250)) on these communities. 16S rRNA gene sequence and metagenomic analyses of bacterial membership and functions revealed dramatic differences betwee

SUBMITTER: Looft T 

PROVIDER: S-EPMC4817603 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature