Extract from a mutant Rhodobacter sphaeroides as an enriched carotenoid source.

ABSTRACT:

Background

The extract Lycogen™ from the phototrophic bacterium Rhodobacter sphaeroides (WL-APD911) has attracted significant attention because of its promising potential as a bioactive mixture, attributed in part to its anti-inflammatory properties and anti-oxidative activity.

Objective

This study aims to investigate the components of Lycogen™ and its anti-inflammatory properties and anti-oxidative activity.

Design and results

The mutant strain R. sphaeroides (WL-APD911) whose carotenoid 1,2-hydratase gene has been altered by chemical mutagenesis was used for the production of a new carotenoid. The strain was grown at 30°C on Luria-Bertani (LB) agar plates. After a 4-day culture period, the mutant strain displayed a 3.5-fold increase in carotenoid content, relative t

SUBMITTER: Wang CC 

PROVIDER: S-EPMC4818355 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature