Reproducibility of carotid-femoral pulse wave velocity in end-stage renal disease patients: methodological considerations.

ABSTRACT:

Background

In end-stage renal disease (ESRD) patients, increased arterial stiffness detected by carotid-femoral pulse wave velocity (cf-PWV) is associated with fatal cardiovascular events and all-cause mortality. Since cf-PWV is an operator-dependent technique, poor reproducibility may be a source of bias in the estimation of arterial stiffness.

Objectives

We assessed the week-to-week reproducibility of cf-PWV and radial artery pulse wave analysis in healthy subjects and ESRD patients. We also determined the extent of patient eligibility, enrollment, acceptance, and comfort.

Methods

In a cohort study design, independent tonometric examinations of carotid, femoral, and radial arteries were conducted in 20 healthy subjects and 15 ESRD patients attending chronic hemodial

SUBMITTER: Rodriguez RA 

PROVIDER: S-EPMC4818522 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature