The association of urinary polycyclic aromatic hydrocarbon biomarkers and cardiovascular disease in the US population.

ABSTRACT:

Background

Polycyclic aromatic hydrocarbons (PAHs) are potent atmospheric pollutants produced by incomplete combustion of organic materials. Pre-clinical and occupational studies have reported a positive association of PAHs with oxidative stress, inflammation and subsequent development of atherosclerosis, a major underlying risk factor for cardiovascular disease (CVD). The aim of the current study is to estimate the association between levels of PAH biomarkers and CVD in a national representative sample of United States (US) adults.

Methods

We examined adult participants (≥20years of age) from the merged US National Health and Nutrition Examination Survey 2001-2010. Logistic regression models were used to estimate the associations of each urinary PAH biomarker and CVD. Post-

SUBMITTER: Alshaarawy O 

PROVIDER: S-EPMC4818691 | biostudies-literature | 2016 Apr-May

REPOSITORIES: biostudies-literature