Ontology highlight
ABSTRACT:
SUBMITTER: Yao J
PROVIDER: S-EPMC4818754 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
EMBO molecular medicine 20160401 4
The nervous and vascular systems, although functionally different, share many common regulators of function maintenance. Long non-coding RNAs (lncRNAs) are important players in many biological processes and human disorders. We previously identified a role of MALAT1 in microvascular dysfunction. However, its role in neurodegeneration is still unknown. Here, we used the eye as the model to investigate the role of MALAT1 in retinal neurodegeneration. We show that MALAT1 expression is significantly ...[more]