Comparative transcriptome analyses of seven anurans reveal functions and adaptations of amphibian skin.

ABSTRACT: Animal skin, which is the tissue that directly contacts the external surroundings, has evolved diverse functions to adapt to various environments. Amphibians represent the transitional taxon from aquatic to terrestrial life. Exploring the molecular basis of their skin function and adaptation is important to understand the survival and evolutionary mechanisms of vertebrates. However, comprehensive studies on the molecular mechanisms of skin functions in amphibians are scarce. In this study, we sequenced the skin transcriptomes of seven anurans belonging to three families and compared the similarities and differences in expressed genes and proteins. Unigenes and pathways related to basic biological processes and special functions, such as defense, immunity, and respiration, were enriched in

SUBMITTER: Huang L 

PROVIDER: S-EPMC4819189 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature