Light-triggered chemical amplification to accelerate degradation and release from polymeric particles.

ABSTRACT: We describe a means of chemical amplification to accelerate triggered degradation of a polymer and particles composed thereof. We designed a light-degradable copolymer containing carboxylic acids masked by photolabile groups and ketals. Photolysis allows the unmasked acidic groups in the polymer backbone to accelerate ketal hydrolysis even at neutral pH.

SUBMITTER: Olejniczak J 

PROVIDER: S-EPMC4819761 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature