Biomarkers and mortality after transient ischemic attack and minor ischemic stroke: population-based study.

ABSTRACT:

Background and purpose

Premature death after transient ischemic attack or stroke is more often because of heart disease or cancer than stroke. Previous studies found blood biomarkers not usefully predictive of nonfatal stroke but possibly of all-cause death. This association might be explained by potentially treatable occult cardiac disease or cancer. We therefore aimed to validate the association of a panel of biomarkers with all-cause death, particularly cardiac death and cancer death, despite the absence of associations with risk of nonfatal vascular events.

Methods

Fifteen biomarkers were measured in 929 consecutive patients in a population-based study (Oxford Vascular Study), recruited from 2002 and followed up to 2013. Associations were determined by Cox regression. Mo

SUBMITTER: Greisenegger S 

PROVIDER: S-EPMC4820048 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature