Carotid angiographic characteristics in the CREST trial were major contributors to periprocedural stroke and death differences between carotid artery stenting and carotid endarterectomy.

ABSTRACT:

Objective

The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) demonstrated a higher periprocedural stroke and death (S+D) rate among patients randomized to carotid artery stenting (CAS) than to carotid endarterectomy (CEA). Herein, we seek factors that affect the CAS-CEA treatment differences and potentially to identify a subgroup of patients for whom CAS and CEA have equivalent periprocedural S+D risk.

Methods

Patient and arterial characteristics were assessed as effect modifiers of the CAS-CEA treatment difference in 2502 patients by the addition of factor-by-treatment interaction terms to a logistic regression model.

Results

Lesion length and lesions that were contiguous or were sequential and noncontiguous extending remote from the bulb were

SUBMITTER: Moore WS 

PROVIDER: S-EPMC4820245 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature