Ligand-Enabled Arylation of γ-C-H Bonds.

ABSTRACT: Pd(II) -catalyzed arylation of γ-C(sp(3) )-H bonds of aliphatic acid-derived amides was developed by using quinoline-based ligands. Various γ-aryl-α-amino acids were prepared from natural amino acids using this method. The influence of ligand structure on reactivity was also systematically investigated.

SUBMITTER: Li S 

PROVIDER: S-EPMC4821162 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature