Treatment complications and survival in advanced laryngeal cancer: a population-based analysis.

ABSTRACT:

Objectives/hypothesis

Primary curative treatment of advanced laryngeal cancer may include surgery or chemoradiation, although recommendations vary and both are associated with complications. We evaluated predictors and trends in the use of these modalities and compared rates of complications and overall survival in a population-based cohort of older adults.

Study design

Retrospective population-based cohort study.

Methods

Using Surveillance Epidemiology and End Results (SEER) cancer registry data linked with Medicare claims, we identified patients over 65 with advanced laryngeal cancer diagnosed 1999 to 2007 who had total laryngectomy (TL) or chemoradiation (CTRT) within 6 months following diagnosis. We identified complications and estimated the impact of treatment on

SUBMITTER: O'Neill CB 

PROVIDER: S-EPMC4821412 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature