Simple and Versatile 3D Printed Microfluidics Using Fused Filament Fabrication.

ABSTRACT: The uptake of microfluidics by the wider scientific community has been limited by the fabrication barrier created by the skills and equipment required for the production of traditional microfluidic devices. Here we present simple 3D printed microfluidic devices using an inexpensive and readily accessible printer with commercially available printer materials. We demonstrate that previously reported limitations of transparency and fidelity have been overcome, whilst devices capable of operating at pressures in excess of 2000 kPa illustrate that leakage issues have also been resolved. The utility of the 3D printed microfluidic devices is illustrated by encapsulating dental pulp stem cells within alginate droplets; cell viability assays show the vast majority of cells remain live, and device t

SUBMITTER: Morgan AJ 

PROVIDER: S-EPMC4822857 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature