HAG regimen improves survival in adult patients with hypocellular acute myeloid leukemia.

ABSTRACT:

Background

Hypocellular acute myeloid leukemia (Hypo-AML) is a rare disease entity. Studies investigating the biological characteristics of hypo-AML have been largely lacking. We examined the clinical and biological characteristics, as well as treatment outcomes of hypo-AML in our institutes over a seven years period.

Design and methods

We retrospectively analyzed data on 631 adult AML patients diagnosed according to the French-American-British (FAB) classification and WHO classification of tumors of haematopoietic and lymphoid tissue, including 43 patients with hypo-AML. Biological variables, treatment outcomes and follow-up data on hypo-AML patients were analyzed.

Results

Out of 631 AML patients, 47 (7.4%) were diagnosed as hypo-AML, out of which 43 patients were ev

SUBMITTER: Hu X 

PROVIDER: S-EPMC4823132 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature