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Geographic variation in the use of adjuvant therapy among elderly patients with resected non-small cell lung cancer.


ABSTRACT:

Objectives

The purpose of this study was to assess to what extent geographic variation in adjuvant treatment for non-small cell lung cancer (NSCLC) patients would remain, after controlling for patient and area-level characteristics.

Materials and methods

A retrospective cohort of 18,410 Medicare beneficiaries with resected, stage I-IIIA NSCLC was identified from the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database. Adjuvant therapies were classified as adjuvant chemotherapy (ACT), postoperative radiation therapy (PORT), or no adjuvant therapy. Predicted treatment probabilities were estimated for each patient given their clinical, demographic, and area-level characteristics with multivariate logistic regression. Area Treatment Ratios were used to es

SUBMITTER: Schroeder MC 

PROVIDER: S-EPMC4823769 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature