Comparative effectiveness of biliary brush cytology and intraductal biopsy for detection of malignant biliary strictures: a systematic review and meta-analysis.

ABSTRACT:

Background

Evaluation of indeterminate biliary strictures typically involves collection and analysis of tissue or cells. Brush cytology and intraductal biopsies that are routinely performed during ERCP to assess malignant-appearing biliary strictures are limited by relatively low sensitivity.

Objective

To study the comparative effectiveness of brushings for cytology and intraductal biopsies in the etiology of biliary strictures.

Design

Meta-analysis.

Setting

Referral center.

Patients

PUBMED and Embase databases were reviewed for studies published to April 2014 where diagnostic correlation of histology was available.

Intervention

Database and review of study findings.

Main outcome measurements

Sensitivity and specificity.

Results

The

SUBMITTER: Navaneethan U 

PROVIDER: S-EPMC4824293 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature