Long-Term Green Tea Supplementation Does Not Change the Human Gut Microbiota.

ABSTRACT:

Background

Green tea catechins may play a role in body weight regulation through interactions with the gut microbiota.

Aim

We examined whether green tea supplementation for 12 weeks induces changes in composition of the human gut microbiota.

Methods

58 Caucasian men and women were included in a randomized, placebo-controlled design. For 12 weeks, subjects consumed either green tea (>0.56 g/d epigallocatechin-gallate + 0.28 ∼ 0.45 g/d caffeine) or placebo capsules. Fecal samples were collected twice (baseline, vs. week 12) for analyses of total bacterial profiles by means of IS-profiling, a 16S-23S interspacer region-based profiling method.

Results

No significant changes between baseline and week 12 in subjects receiving green tea or placebo capsules, and no sig

SUBMITTER: Janssens PL 

PROVIDER: S-EPMC4824458 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature