Preoperative induction therapy for locally advanced thymic tumors: a retrospective analysis using the ChART database.

ABSTRACT:

Background

To evaluate the role of preoperative induction therapy on prognosis of locally advanced thymic malignancies.

Methods

Between 1994 and 2012, patients received preoperative induction therapies (IT group) in the Chinese Alliance for Research in Thymomas (ChART) database, were compared with those having surgery directly after preoperative evaluation (DS group). All tumors receiving induction therapies were locally advanced (clinically stage III-IV) before treatment and those turned out to be in pathological stage I and II were considered downstaged by induction. Clinical pathological characteristics were retrospectively analyzed. To more accurately study the effect of induction therapies, stage IV patients were then excluded. Only stage I-III tumors in the IT group an

SUBMITTER: Wei Y 

PROVIDER: S-EPMC4824724 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature